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BCRF Grantee Since


Donor Recognition

The Estée Lauder Companies North America Supply Chain & Operating Facilities Award

Area(s) of Focus

Monica N. Fornier, MD

Associate Member at the Breast Medicine Service
Memorial Sloan Kettering Cancer Center
Associate Professor, Weill Cornell Medical College
New York, New York

Current Research

Metabolomics is a relatively new scientific field in cancer, but one with great potential. It focuses on the molecules that are created during normal cellular processes. These molecules, called metabolites, are often found in the blood or other bodily fluids and can be used to determine what kinds of processes are occurring in the cell. Changes in the types and amounts of metabolites occur in cancer and can provide important clues about the cancer. Drs. Fornier and Biganzoli are studying whether metabolites in blood of women with early stage breast cancer can help predict the likelihood of breast cancer recurrence. They have collect 730 blood samples from patients with early breast cancer, and 109 samples from patients with metastatic disease, from two trials run in Southeast Asia. Their analysis of these samples shows a clear separation in metabolic profile between early and late disease. Their current efforts are aimed at refining and interpreting these differences, in order to define the metabolic signature of a patient who is likely to suffer a relapse. Part of these efforts includes combining metabolomic risk analysis with existing models such as OncotypeDX or AdjuvantOnline. Results from these projects could help identify women with early breast cancer who are at higher risk of disease recurrence and would have the most benefit from chemotherapy after their breast cancer surgery.


Dr. Monica Fornier is an Associate Member at the Breast Medicine Service of Memorial Sloan Kettering Cancer Center and Assistant Professor at Weil Cornell Medical College. She specializes in the treatment of breast cancer. She is also an Assistant Professor at the Weill Medical College of Cornell University, New York Presbyterian Hospital

Dr. Fornier graduated summa cum laude at the University of Milan (Italy); she pursued her Oncology fellowship at the National Cancer Institute of Milan, under the mentorship of Dr. Gianni Bonadonna, and a second fellowship at Memorial Sloan Kettering Cancer Center in New York, under the mentorship of Dr. Larry Norton. She is currently a member of the Faculty at Memorial Sloan Kettering Cancer Center, where she conducts clinical research in breast cancer. Dr. Fornier has been involved in the development and conduction of numerous clinical trials assessing novel drugs and drug scheduling strategies for the treatment of breast cancer, both in the adjuvant and metastatic setting.

Dr Fornier is an active member of various national and international scientific groups, including the American Society of Clinical Oncology and the European Society of Medical Oncology. Dr Fornier has numerous publications to her name and has presented data at international meetings.