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BCRF Grantee Since

2008

Gad Rennert, MD, PhD

Director, Clalit National Israeli Cancer Control Center
Professor and Chairman, Department of Community Medicine
Carmel Medical Center
Haifa, Israel

Current Research

Breast cancer outcomes and response to treatment are affected by multiple factors, including demographic characteristics (such as age at diagnosis and ethnic group), environmental exposures (such as reproductive patterns and obesity) and biological/genetic characteristics of the patient. Dr. Rennert’s BCRF research aims to identify sub-sets of women with differing patterns of disease behavior, such as recurrence in the same or contralateral breast, metastases (and site of metastases) and death due to breast cancer. Dr. Rennert is studying these sub-groups for differences in their tumor molecular characteristics, inherited genetic mutations and environmental exposures in an effort to better understand the causes of breast cancer. Participants from this study are also part of the Game-On initiative of the National Cancer Institute where samples representing different populations will be studied for a large variety of genetic variations called SNPs that may be important in predicting breast cancer risk. Dr. Rennert and his colleagues expect to be able to study more than 2,000 women and gain understanding of the molecular underpinnings of these cases.

Bio

Prof. Gad Rennert is the chairman of the Carmel Medical Center Department of Community Medicine and Epidemiology since 1992. He is a professor and the head of public health and epidemiology teaching group at the Technion Faculty of Medicine.

Prof. Rennert is also the Director of the National Israeli Cancer Control Center and the Department of Epidemiology and Disease Prevention of Clalit and is also leading its National Personalized Medicine Program offering testing, advice and policy on individualized molecular testing which dictates cancer risk and suitability for cancer treatments. He is responsible for the national breast and colorectal cancer detection programs in Israel and is a member of the National Oncology Council.

In 1984, Prof. Rennert received his medical degree from Ben-Gurion Medical School. He received his PhD in Public Health from the University of North Carolina. He focuses his studies on understanding the behavioral and biological causes of cancer, with special emphasis on gene-environment interactions. He is an invited speaker in key conferences in the world, such as the Personalized Medicine World Conference, UPCP, American Society of Clinical Oncology, American Association of Cancer Research, St. Galen Cancer Prevention conference and San Antonio Breast Cancer Symposium.

In addition to his activities at the Technion, Dr. Rennert is a reviewer for more than thirty international journals, is an associate editor of two and serves on ten of their editorial boards. He has published more than 200 papers among them in leading journals such as the NEJM, Science and Nature.