Professor of Medicine, Harvard Medical School
Chief, Division of Women's Cancers
Director, Breast Oncology Center
Dana-Farber Cancer Institute
Although significant advances have been made in the treatment of metastatic breast cancer, nearly all women with stage IV breast cancer will die of their disease. Drs. Winer and Lin are actively pursuing new and promising alternatives for advanced breast cancer. Over the past several years, with support from the BCRF they have completed multiple clinical trials to test new treatments for advanced breast cancer, including trials for patients with cancer that has metastasized (spread) to the brain. Drs Winer and Lin have also developed several new laboratory models for breast cancer brain metastases, which they are using to test new drug combinations to identify the most promising combinations for future clinical use. In addition, the investigators have expanded their efforts in metastatic breast cancer more broadly through the EMBRACE (Ending Metastatic Breast Cancer for Everyone) study, which collects blood, tumor tissue, and clinical data and will speed collaborations between the laboratory and clinic. These studies represent a major effort to better understand and treat patients with breast cancer and brain metastases, an area that until recently had been almost entirely neglected in drug development.
Eric P. Winer, MD, is Professor of Medicine at Harvard Medical School and Chief, Division of Women's Cancers and the Thompson Senior Investigator in Breast Cancer Research at Dana-Farber Cancer Institute. He is also Co-Chair of the Breast Committee of the Alliance for Clinical Trials. Dr. Winer has devoted his professional career to the treatment of individuals with breast cancer and breast cancer research. He has designed and led phase I, II, and III clinical trials. Dr. Winer has collaborated closely throughout his career with psychosocial, health services, basic, and translational researchers. He is the Principal Investigator of the Dana-Farber/Harvard Cancer Center SPORE in Breast Cancer.
Dr. Winer is a graduate of Yale College, with a degree in History and Russian/East European Studies. He subsequently obtained his medical degree from Yale School of Medicine, followed by training in internal medicine at Yale. He completed a fellowship in medical oncology at Duke University Medical Center and remained on the Duke Faculty until 1997, when we moved to Dana-Farber Cancer Institute in Boston to assume the role of Director of the Breast Oncology Center.