When Good Cells Go Bad

The third group of projects focused on finding the cause(s) of breast cancer is on irregular cellular activities, or "When Good Cells Go Bad," which seem to occur randomly. Researchers have determined that only 5-10% of breast cancers are due to an abnormality inherited from a parent, so there is considerable uncertainty over what causes breast cancer. BCRF researchers have contributed significantly to our understanding in this area. Thanks to their advances, most breast cancer cases are manageable or even "curable."

Grantees working in this group are:

Stuart A. Aaronson, MD

Joaquin Arribas, PhD

Jill Bargonetti, PhD

Isabelle Bedrosian, MD

Robert Benezra, PhD

Ross Berkowitz, MD, Ursula Matulonis, MD, and Zhigang Charles Wang, MD, PhD

Julienne Bower, PhD and Steven W. Cole, PhD

Powel H. Brown, MD, PhD

Joan S. Brugge, PhD

Fatima Cardoso, MD, John M.S. Bartlett, PhD, Sharon Giordano, MD, MPH, and Peggy L. Porter, MD

Jenny Chang, MD

Susan E. Clare, MD, PhD and Anna Maria Storniolo, MD

Michael F. Clarke, MD

Andrew Dannenberg, MD

Charis Eng, MD, PhD, FACP

Laura J. Esserman, MD, MBA

Zhen Fan, MD

Heide L. Ford, PhD

William J. Gradishar, MD and Vincent L. Cryns, PhD

Rachel Hazan, PhD and Larry Norton, MD

Gabriel N. Hortobagyi, MD and Mien-Chie Hung, PhD

Clifford Hudis, MD

J. Dirk Iglehart, MD, Andrea Richardson, MD, PhD, and Zhigang Charles Wang, MD, PhD

Johanna A. Joyce, PhD

Titia de Lange, PhD

Eva Y.-H.P. Lee, PhD

Arnold J. Levine, PhD and Kim Hirshfield, MD, PhD

Rosette Lidereau, PhD

Marc E. Lippman, MD

David M. Livingston, MD

Sofia Merajver, MD, PhD

Kathy D. Miller, MD

Gordon B. Mills, MD, PhD

Marsha A. Moses, PhD

Hyman B. Muss, MD

Paul M. Nurse, PhD

Ben Ho Park, MD, PhD

Charles M. Perou, PhD

Richard Pestell, MD, PhD

Kornelia Polyak, MD, PhD

Sir Bruce Ponder, MB, PhD and Christina Curtis, PhD

Michael F. Press, MD, PhD

Hope S. Rugo, MD

Mary Sehl, MD

Joyce Slingerland, MD

Ian E. Smith, MD, FRCP, FRCPE and Mitch Dowsett, PhD, BSc

Ilan Tsarfaty, PhD and George F. Vande Woude, PhD

Geoffrey M. Wahl, PhD

Robert A. Weinberg, PhD

Stephen J. Weiss, MD