Moshe Shike, MD

2009-2010 BCRF Project:
Dr. Shike's study of 132 breast cancer patients (both pre- and post-menopausal) who are scheduled to undergo surgery, aims to determine whether specific molecular markers and genes associated with breast cancer can be altered by a diet rich in soy. This trial has completed recruitment and final data analysis is underway. Testing of the blood samples demonstrated that patients who were in the soy group had a significant elevation in the blood levels of soy components (genistein and daidzein), while the patients in the placebo group had no change. This indicates compliance with soy supplementation. Analysis of the effect of soy on breast cancer tissue markers is currently being performed.

Bio:
Moshe Shike is an attending physician at Memorial Sloan-Kettering Cancer Center and a professor of medicine at Cornell University Medical College. He is the past director or the Cancer Prevention and Wellness Program at MSKCC, which he established in 1999. He graduated from Tel Aviv University School of Medicine in 1974, and completed his residency in Internal Medicine at the Harvard School of Medicine in addition to a fellowship in Gastroenterology and Nutrition at the University of Toronto.

Dr Shike joined the Department of Medicine at Memorial Sloan-Kettering Cancer Center in 1981. He focused his research on nutrition in cancer, and has been examining the role of diet and specific dietary factors on various stages of cancer development. His research also includes studies on nutrition support in cancer patients including enteral and parenteral nutrition.